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Recombinant Human Platelet Derived Growth Factor Bb

About Recombinant Human Platelet Derived Growth Factor Bb

Recombinant Human Platelet Derived Growth Factor Bb belongs to the platelet-derived growth factors (PDGFs) class used to treat diabetic foot ulcers in people with good blood flow in the legs and feet. A diabetic foot ulcer is a common complication of diab­etes. Ulcers are formed due to skin tissue breakdown and exposure to underneath layers. Diabetic foot ulcers commonly develop under the big toes and balls of the feet. Also, they can affect the feet down to the bones.

Recombinant Human Platelet Derived Growth Factor Bb contains Recombinant Human Platelet-Derived Growth Factor BB (Becaplermin), which stimulates the growth of cells involved in wound healing. Therefore, it helps treat ulcers of the legs or foot in people with diabetes.

Recombinant Human Platelet Derived Growth Factor Bb is only for external use. Use Recombinant Human Platelet Derived Growth Factor Bb as prescribed by your doctor. You are advised to use Recombinant Human Platelet Derived Growth Factor Bb for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience burning at the application site and red skin rash. Most of these side effects of Recombinant Human Platelet Derived Growth Factor Bb do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are known to be allergic to Recombinant Human Platelet Derived Growth Factor Bb or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please consult your doctor before using Recombinant Human Platelet Derived Growth Factor Bb. Avoid using Recombinant Human Platelet Derived Growth Factor Bb if you have a skin tumor at the site of the application. The size of the ulcer must be checked by your doctor every 1 to 2 weeks so that the dose may be adjusted according to the size of the ulcer.

Uses of Recombinant Human Platelet Derived Growth Factor Bb

Recombinant Human Platelet Derived Growth Factor Bb is used to treat Diabetic foot ulcers. The detailed uses of Recombinant Human Platelet Derived Growth Factor Bb are as follows: • Diabetic Foot Ulcers: Recombinant Human Platelet Derived Growth Factor Bb is used for treating lower extremity diabetic neuropathic ulcers that extend into subcutaneous tissue and have adequate blood supply. • Granulation Tissue Formation: Recombinant Human Platelet Derived Growth Factor Bb stimulates fibroblast activity to build new tissue and blood vessels.

Medicinal Benefits

Recombinant Human Platelet Derived Growth Factor Bb contains Recombinant Human Platelet-Derived Growth Factor BB (Becaplermin), used to treat diabetic foot ulcers in people with good blood flow in the legs and feet. Recombinant Human Platelet Derived Growth Factor Bb stimulates the growth of cells involved in wound healing. Therefore, it helps treat ulcers of the legs or feet in people with diabetes. Recombinant Human Platelet Derived Growth Factor Bb is used along with other ulcer care practices, such as good wound care to treat diabetic foot ulcers.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety. • Take a small amount of Recombinant Human Platelet Derived Growth Factor Bb onto a firm, clean, non-absorbable surface like wax paper. Then spread it evenly as a thin layer over the surface of the foot ulcer with the help of a clean cotton swab, tongue depressor or any other application aid. • Cover the treated area with a gauze dressing moistened with saline.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Recombinant Human Platelet Derived Growth Factor Bb

  • Burning at the site of application
  • Red skin rash

Drug Warnings

If you are known to be allergic to Recombinant Human Platelet Derived Growth Factor Bb or any other medicines, please tell your doctor. Avoid using Recombinant Human Platelet Derived Growth Factor Bb if you have a skin tumor at the site of the application. The size of the ulcer must be checked by your doctor every 1 to 2 weeks so that the dose may be adjusted according to the size of the ulcer. You are recommended to cover the treated area with a gauze dressing moistened with saline. Avoid contact of Recombinant Human Platelet Derived Growth Factor Bb with mouth, eyes, or vagina. Do not touch the tip of the tube to the ulcer or any other surface. In case Recombinant Human Platelet Derived Growth Factor Bb comes in contact with these areas accidentally, rinse with warm water thoroughly. If you are pregnant or breastfeeding, please consult your doctor before using Recombinant Human Platelet Derived Growth Factor Bb.

Drug Interactions

Drug-Drug Interaction: No interactions found.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have cancer, skin tumor or poor blood flow to lower legs and feet, please inform your doctor before taking Recombinant Human Platelet Derived Growth Factor Bb.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    The interaction of Recombinant Human Platelet Derived Growth Factor Bb with alcohol is unknown. Please consult a doctor before consuming alcohol while using Recombinant Human Platelet Derived Growth Factor Bb.

  • Safety Warning

    Pregnancy

    caution

    Please consult a doctor if you are pregnant. Recombinant Human Platelet Derived Growth Factor Bb is given to pregnant women if the doctor thinks the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    caution

    It is unknown whether Recombinant Human Platelet Derived Growth Factor Bb is excreted in human milk. Therefore, Recombinant Human Platelet Derived Growth Factor Bb is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

  • Safety Warning

    Driving

    safe if prescribed

    Recombinant Human Platelet Derived Growth Factor Bb usually does not affect your ability to drive or operate machinery.

  • Safety Warning

    Liver

    safe if prescribed

    Please consult a doctor if you have any concerns about using Recombinant Human Platelet Derived Growth Factor Bb in patients with liver problems.

  • Safety Warning

    Kidney

    safe if prescribed

    Please consult a doctor if you have any concerns about using Recombinant Human Platelet Derived Growth Factor Bb in patients with kidney problems.

  • Safety Warning

    Children

    unsafe

    Recombinant Human Platelet Derived Growth Factor Bb is not recommended for children below 16 years as the safety and effectiveness were not established.

Habit Forming

No

Diet & Lifestyle Advise

  • Do not put weight on the affected leg and foot.
  • Adequately trim your toenails but not too short.
  • Regularly change your socks and wear proper-fitting shoes.
  • Keep your feet dry and moisturized.
  • Regularly wash your feet.
  • Consult a doctor if you have corn and also for callus removal.
  • Wear shoe inserts to prevent calluses and corns.
  • Wear foot braces, compression wraps or casts to protect your feet.

Patients Concern

Disease/Condition Glossary

Diabetic foot ulcers: It is a common complication of diab­etes. Ulcers are formed due to the breakdown of skin tissue and exposure of underneath layers. Diabetic foot ulcers commonly develop under the big toes and balls of the feet. Also, they can affect the feet down to the bones. The primary sign of diabetic foot ulcer is drainage from the foot that stains socks or leaks out in the shoe. Other symptoms include redness, irritation, unusual swelling, and odors from 1 or both feet. Sometimes, there may be no symptoms until the ulcer has become infected. Treatment includes medication and surgical procedures.

FAQs

Recombinant Human Platelet Derived Growth Factor Bb contains Becaplermin, a platelet-derived growth factor that stimulates the growth of cells involved in wound healing. Thus, it helps treat ulcers of the legs or feet in people with diabetes.

Recombinant Human Platelet Derived Growth Factor Bb is not recommended for treating pressure ulcers or ulcers caused by poor blood flow. It is only used to treat diabetic foot ulcers in patients with a good blood supply.

You are recommended to use Recombinant Human Platelet Derived Growth Factor Bb for as long as your doctor has prescribed it. However, if the size of the ulcer is not a minimum of 1/3rd smaller in size after using Recombinant Human Platelet Derived Growth Factor Bb for 10 weeks or if the ulcer is not healed completely after 20 weeks, please consult a doctor.

Recombinant Human Platelet Derived Growth Factor Bb may temporarily cause a red skin rash. If the rash persists or worsens, please consult a doctor.

Recombinant Human Platelet Derived Growth Factor Bb is not recommended for patients suffering from skin cancer at the application site. Therefore, if you have cancer, inform your doctor before using Recombinant Human Platelet Derived Growth Factor Bb.

Recombinant Human Platelet Derived Growth Factor Bb belongs to the platelet-derived growth factors (PDGFs) class, which are used to treat diabetic foot ulcers in people with good blood flow in their legs and feet.

The common side effects of Recombinant Human Platelet Derived Growth Factor Bb may include burning at the application site and red skin rash. Most of these side effects of Recombinant Human Platelet Derived Growth Factor Bb do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

Available Medicines for

Recombinant Human Platelet Derived Growth Factor Bb

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